Case Report

Vol. 25 No. 2 (2016): Turkish Journal of Nephrology Türk Nefroloji Derneği Dergisi TND Dergisi

Non-Caseating Granulamatus Nephritis: Rare Sign of Sarcoidosis

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Vedat GENÇER
İbrahim GÜNEY
Raziye YAZICI
Hasan ESEN
Uysaler ASLAN
Özden BÖLÜKBAŞ

Abstract

Sarcoidosis is chronic multisystem granulomatous disease. It can rarely cause renal structural and functional damage. Renal impairment is mostly due to the calcium metabolism and associated with hypercalciuria, nephrolithiasis and nephrocalcinosis. Non-caseating granulomatous nephritis can also be seen in few patients. We diagnosed non-caseating granulomatous nephritis with renal biopsy in a 50-year-old female pulmonary sarcoidosis case. Steroid treatment was immediately started and there was a significant decrease in proteinuria and creatinine after a month. Proteinuria and serum creatinine increase are important in patients with sarcoidosis and treatment must be started immediately to prevent end-stage renal failure.


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