Prevalence of Nondiabetic Glomerular Diseases in Patients with Type 2 Diabetes Mellitus

Abstract

Objective: Despite notable progress made in the past decade in research and clinical practice in the treatment of diabetic kidneydisease, the diagnostic and prognostic significance of proteinuria in patients with diabetes has imposed constant challenges to nephrologists and diabetologists. The main goal of the study was to assess the prevalence of nondiabetic kidney disease among proteinuric patients with type 2 diabetes mellitus.

Methods: We evaluated kidney l biopsy findings obtained from 82 diabetic patients to assess the etiology of proteinuria.

Results: A review of histopathological results indicated features of diabetic nephropathy in 29 of these persons (36.7%). In 21 diabetic nephropathy patients (71.4%), proteinuria was within the nephrotic range. Nondiabetic kidney disease was discovered in 51 persons (62.2%), whereas in 2 cases, the exact type of glomerular disease has not been established.

Conclusion: We conclude from these results that diagnostic kidney biopsy is justified in type 2 diabetes patients with proteinuria since the prevalence of nondiabetic kidney disease is high in these subjects and adequate histopathological assessment could improve the management of their kidney disease.

Cite this article as: Sroka M, Lis Ł, Witkiewicz W, Uchmanowicz I, Hruby Z. Prevalence of nondiabetic glomerular diseases in patients with type 2 diabetes mellitus. Turk J Nephrol. 2023;32(2):136-139.