DIALYSIS AMILOIDOSIS AND CARPAL TUNNEL SYNDROME
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Abstract
ESRD patients' expected survival increased with the amelioration of the quality of care in both long term HD and CAPD. Beta -2 microglobulin type dialysis amiloidosis and its clinical manifestations like osteo articular, norologic symptoms and signs and CTS are frequently seen in these patients especially those with longer dialysis durations.
In these study CTS which is the most important finding of DA, frequency and the associated parameters are evaluated.
The presence of CTS was evaluated by EMG in 48 patients (29 male, 19 female) undergoing chronic dialysis (30 HD, 18 CAPD) . The CTS was ascertained in 18patients (37,5 %). The associations between CTS and patients age , sex , dialysis durations, arthritis, arthralgias, symptoms and signs of CTS, levels of serum ferritine CRP and intact PTH were evaluated in all patients.
As a cosequence about all of these parameters only serum ferritine levels had a strong statistically meaningfull association with CTS. (p=0,02)