Original Article

Vol. 21 No. 3 (2012): Turkish Journal of Nephrology Türk Nefroloji Derneği Dergisi TND Dergisi

The Relationship Between Bone Mineral Densitometry and Vascular Calcifi cation in Peritoneal Dialysis Patients

Main Article Content

Kültigin TÜRKMEN
Fatih Mehmet ERDUR
Orhan ÖZBEK
Hatice KAYIKÇIOĞLU
Mustafa SAĞLAM
Halil Zeki TONBUL

Abstract

OBJECTIVE: Vascular calcifi cation (VC) and disturbed bone mineral metabolism (BMM) are commonly seen in patients with end-stage renal disease (ESRD). Fetuin-A has been found to be signifi cantly low in ESRD patients. The aim of our study was to investigate the relation between coronary artery calcifi cation, BMM and fetuin-A in peritoneal dialysis (PD) patients.



MATERIAL and METHODS: 46 PD (M/F=28/18) patients were included in the study. Coronary artery calcifi cation scoring (CACS) was performed by multi slice computed tomography. The patients were divided into 4 groups according to their CACS values as Group 1 (CACS: 0), Group 2 (CACS:1- 99), Group 3 (CACS:100-399) and Group 4 (CACS: ≥400). Serum levels of fetuin-A were measured. Bone mineral densitometry was measured by dual energy X-ray absorptiometer (DEXA).



RESULTS: There was a statistically signifi cant difference difference between CACS and femur T scores in PD patients. Femur T scores were found to be decreased while CACS values are increased. We could not fi nd any differences in terms of CACS when we separated patients according to T scores greater or lower than -2. Osteopenic patients were found to be older and they also had low fetuin-A levels.



CONCLUSION: We found an important relationship between CACS and bone mineralization in PD patients.


Article Details