IgA Nephropathy and Psoriasis in a Child

Abstract

IgA nephropathy is the most common primary glomerulonephritis worldwide. Painless macroscopic hematuria is frequent in children and often coincides with infections of the upper respiratory tract and/ or digestive system. The distinctive carbohydrate side chains of IgA1 molecules play an important role in the pathogenesis of IgA nephropathy. Defi nitive diagnosis of IgA nephropathy requires evaluation of a renal biopsy specimen. Psoriasis is also a common childhood chronic skin disease with changes in epidermal differentation and proliferation. There are also a few literature reports on the co-existence of IgA nephropathy and psoriasis mainly in adult patients. Herein, we report a child with psoriasis who was diagnosed as Ig A nephropathy after periods of painless hematuria.