Gabapentin Toxicity in Patients with Chronic Kidney Disease; Series of Our Cases
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Abstract
Gabapentin is an anticonvulsant with analgesic and anxiolytic effects and also an agent used for treatment of a variety of chronic neuropathic pains. Because gabapentin is eliminated solely through the kidney, kidney failure poses a risk for gabapentin accumulation and toxicity. Gabapentin toxicity in kidney failure hasn’t been clearly proved till now. We want to emphasize the gabapentin toxicity on fi ve cases with chronic kidney diasease at the present study.