Sarcoidosis Presenting with Membranous Nephropathy in a Patient with Hypertensive Nephropathy: Case Report

Abstract

Sarcoidosis is a systemic granulomatous disease that primarily involves the lung but may also have renal involvement. We present a hypertensive nephrosclerosis case found to have sarcoidosis after membranous nephropathy was diagnosed. A 57-year-old female patient was admitted due to nephrotic syndrome. She had a history of hypertension for 5 years. Fundus examination was consistent with grade 2 hypertensive retinopathy. Kidney biopsy was performed because of nephrotic syndrome and impaired renal function and revealed membranous nephropathy. Sarcoidosis was diagnosed while secondary causes of membranous nephropathy were investigated. Nephrotic syndrome was improved with steroid treatment in 6 months. In conclusion, a sarcoidosis case initially presenting with membranous nephropathy is an uncommon manifestation. Secondary causes of membranous nephropathy must be carefully investigated.